Product Overview
Polmacoxib | T21294 | TargetMol Chemicals
CAS: 301692-76-2
Smiles: CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O
Formula: C18H16FNO4S
Pathway: Immunology/Inflammation|||Metabolism|||Neuroscience
Target: COX|||Carbonic Anhydrase
Receptor: N/A
Bioactivity: Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
Molecular Weight: 361, 39