Product Overview
Pomalidomide-PEG1-C2-N3 | T17904 | TargetMol Chemicals
CAS: 2271036-44-1
Smiles: [N-]=[N+]=NCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Formula: C17H18N6O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Pomalidomide-PEG1-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology. Pomalidomide-PEG1-C2-N3 can be used to design a selective CDK6 PROTAC degrader CP-10. CP-10 induces the degradation of CDK6 with an DC50 of 2.1 nM[1].
Molecular Weight: 386, 368
