Product Overview
Ponatinib | T2372 | TargetMol Chemicals
CAS: 943319-70-8
Smiles: CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)CC1
Formula: C29H27F3N6O
Pathway: Angiogenesis|||Autophagy|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR|||Bcr-Abl|||PDGFR|||Src|||c-Kit|||Autophagy
Receptor: N/A
Bioactivity: Ponatinib is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).
Molecular Weight: 532, 571
