Product Overview
Posaconazole hydrate | T23174 | TargetMol Chemicals
CAS: 1198769-38-8
Smiles: O.[H][C@@](C)(O)[C@]([H])(CC)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@]3([H])CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O
Formula: C37H44F2N8O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14É‘ demethylase inhibitor (IC50: 0.25 nM). Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme.
Molecular Weight: 718, 807
