Product Overview
Poziotinib | T2630 | TargetMol Chemicals
CAS: 1092364-38-9
Smiles: COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
Formula: C23H21Cl2FN4O3
Pathway: Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR|||HER
Receptor: N/A
Bioactivity: Poziotinib(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).
Molecular Weight: 491, 34
