Product Overview
PPY A | T23182 | TargetMol Chemicals
CAS: 875634-01-8
Smiles: COc1ccccc1-c1c[nH]c2ncc(cc12)-c1cncc(c1)C(=O)N(C)C
Formula: C22H20N4O2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: PPY A is an effective inhibitor of T315l mutant and wild-type Abl kinases (IC50: 9 and 20 nM, respectively). PPY A also inhibits the growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene.
Molecular Weight: 372, 428
