Product Overview
Praeruptorin C | T6S1418 | TargetMol Chemicals
CAS: 72463-77-5
Smiles: C\C=C(\C)C(=O)O[C@@H]1[C@H](OC(=O)CC(C)C)c2c(OC1(C)C)ccc1ccc(=O)oc21
Formula: C24H28O7
Pathway: Membrane transporter/Ion channel|||Metabolism|||oxidation-reduction
Target: Antioxidant|||Calcium Channel
Receptor: N/A
Bioactivity: 1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors and regulating the Bcl-2 family. 3. Praeruptorin C can reduce vascular hypertrophy in isolated rat hypertrophied smooth muscle cells, and this is associated with improvement of smooth muscle cells [Ca2+]i level, nitric oxide content and cellular signal transdution of protein kinase C and Gi.
Molecular Weight: 428, 481
