Product Overview
Pralatrexate | T6120 | TargetMol Chemicals
CAS: 146464-95-1
Smiles: Nc1nc(N)c2nc(CC(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
Formula: C23H23N7O5
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||DHFR|||Antifolate|||TAM Receptor
Receptor: N/A
Bioactivity: Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
Molecular Weight: 477, 481
