Product Overview
Praliciguat | T16569 | TargetMol Chemicals
CAS: 1628730-49-3
Smiles: OC(CNc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1)(C(F)(F)F)C(F)(F)F
Formula: C21H14F8N6O2
Pathway: GPCR/G Protein|||Others
Target: Others|||Guanylate cyclase
Receptor: N/A
Bioactivity: Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
Molecular Weight: 534, 37