Product Overview
Praziquantel | T1435 | TargetMol Chemicals
CAS: 55268-74-1
Smiles: O=C(C1CCCCC1)N1CC2N(CCc3ccccc23)C(=O)C1
Formula: C19H24N2O2
Pathway: Membrane transporter/Ion channel|||Metabolism|||Microbiology/Virology
Target: Calcium Channel|||Antibiotic|||Parasite
Receptor: N/A
Bioactivity: Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.
Molecular Weight: 312, 413
