Product Overview
Prexasertib dihydrochloride | T4327 | TargetMol Chemicals
CAS: 1234015-54-3
Smiles: Cl.Cl.COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Formula: C18H21Cl2N7O2
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||MAPK|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||Chk|||S6 Kinase
Receptor: N/A
Bioactivity: Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
Molecular Weight: 438, 31
