Product Overview
Pristimerin | T4S1050 | TargetMol Chemicals
CAS: 1258-84-0
Smiles: COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
Formula: C30H40O4
Pathway: Microbiology/Virology|||NF-Κb
Target: NF-κB|||Antibacterial
Receptor: N/A
Bioactivity: 1. Pristimerin has anticancer activity, treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
Molecular Weight: 464, 646
