Product Overview
Proadrenomedullin (1-20), human | TP1490 | TargetMol Chemicals
CAS: 150238-87-2
Smiles:
Formula: C112H178N36O27
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
Molecular Weight: 2460, 84
