Product Overview
Propargyl-PEG1-acid | T16583 | TargetMol Chemicals
CAS: 55683-37-9
Smiles: OC(=O)CCOCC#C
Formula: C6H8O3
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib-based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 μM[1].
Molecular Weight: 128, 127
