Product Overview
Propargyl-PEG4-acid | T16614 | TargetMol Chemicals
CAS: 1415800-32-6
Smiles: OC(=O)CCOCCOCCOCCOCC#C
Formula: C12H20O6
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1].
Molecular Weight: 260, 286
