PROTAC RAR Degrader-1 | T18635

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TMC-T18635
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Product Overview

PROTAC RAR Degrader-1 | T18635 | TargetMol Chemicals

CAS: 1351169-27-1

Smiles: O=C(O)C1=CC=C(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)C=C1OCCCNC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)=O

Formula: C51H72N4O11

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

Molecular Weight: 917, 14

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