Product Overview
PRX-07034 hydrochloride | T8720 | TargetMol Chemicals
CAS: 903580-39-2
Smiles: Cl.COc1cc(Cl)cc(C(C)Nc2cc(ccc2S(C)(=O)=O)N2CCNCC2)c1OC
Formula: C21H29Cl2N3O4S
Pathway: GPCR/G Protein|||Neuroscience
Target: 5-HT Receptor
Receptor: N/A
Bioactivity: PRX-07034 is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.
Molecular Weight: 490, 44
