Pseurotin A | TN4838

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TMC-TN4838
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Pseurotin A | TN4838 | TargetMol Chemicals

CAS: 58523-30-1

Smiles: CC\C=C/[C@H](O)[C@H](O)C1=C(C)C(=O)[C@@]2(O1)[C@@H](O)[C@](NC2=O)(OC)C(=O)c1ccccc1

Formula: C22H25NO8

Pathway: Microbiology/Virology

Target: Antifection

Receptor: N/A

Bioactivity: Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 values of 220 and 112 microg ml(-1), respectively. Pseurotin A shows to be active against the proliferation of four different glioma cells with IC50 values of 0.51-29.3 uM, the targeting multiple metabolic enzymes might be one of the antiglioma mechanisms of pseurotin A.

Molecular Weight: 431, 44

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