Product Overview
PUMA BH3 | TP1724 | TargetMol Chemicals
CAS: TP1724
Smiles:
Formula: C128H202N42O43S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Molecular Weight: 3049, 3
