Pyrazofurin | T16690

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TMC-T16690
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Product Overview

Pyrazofurin | T16690 | TargetMol Chemicals

CAS: 30868-30-5

Smiles: NC(=O)c1n[nH]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O

Formula: C9H13N3O6

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Pyrazofurin is a pyrimidine nucleoside analogue, inhibits cell proliferation and DNA synthesis in cells by inhibiting UMP synthase. Pyrazofurin is a sensitive orotate-phosphoribosyltransferase inhibitor (IC50s between 0.06-0.37 μM in the cell lines Hep-2, HNSCC-14B, and HNSCC-14C).

Molecular Weight: 259, 218

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