Product Overview
QS11 | T4022 | TargetMol Chemicals
CAS: 944328-88-5
Smiles: OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
Formula: C36H33N5O2
Pathway: GPCR/G Protein
Target: GTPase
Receptor: N/A
Bioactivity: QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
Molecular Weight: 567, 693
