Product Overview
Quiflapon | T16087 | TargetMol Chemicals
CAS: 136668-42-3
Smiles: CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12
Formula: C34H35ClN2O3S
Pathway: Apoptosis|||Immunology/Inflammation
Target: Apoptosis|||FLAP
Receptor: N/A
Bioactivity: Quiflapon causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively).
Molecular Weight: 587, 18
