Product Overview
Quinacrine (hydrochloride hydrate) | T23210 | TargetMol Chemicals
CAS: T23210
Smiles: ClC1=CC=C2C(NC(C)CCCN(CC)CC)=C3C(C=CC(OC)=C3)=NC2=C1.Cl.Cl.O
Formula: C23H30ClN3O·2HCl [XH2O]
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM） and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 μM). As an effective riboflavin antagonist, quinacrine associates with the riboflavin-binding protein (Ki: 6.7 μM). Voltage-dependent sodium channels play a vital role in action potential initiation and propagation in excitable cells, including muscle, nerve, and neuroendocrine cell types.
Molecular Weight: 472, 9
