Product Overview
Quisinostat | T6055 | TargetMol Chemicals
CAS: 875320-29-9
Smiles: Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
Formula: C21H26N6O2
Pathway: Apoptosis|||Autophagy|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: Apoptosis|||HDAC|||Autophagy
Receptor: N/A
Bioactivity: Quisinostat (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7.
Molecular Weight: 394, 479
