Product Overview
QWF | TP1946 | TargetMol Chemicals
CAS: 126088-82-2
Smiles:
Formula: C38H43N5O8
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Tripeptide substance P (SP) antagonist (IC50 = 90 μM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo.
Molecular Weight: 697, 78