Product Overview
(R)-(-)-Gossypol | T6314 | TargetMol Chemicals
CAS: 90141-22-3
Smiles: CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
Formula: C30H30O8
Pathway: Apoptosis|||Autophagy
Target: BCL|||Autophagy
Receptor: N/A
Bioactivity: AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM.
Molecular Weight: 518, 562
