R306465 | T21324

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TMC-T21324
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Product Overview

R306465 | T21324 | TargetMol Chemicals

CAS: 604769-01-9

Smiles: ONC(=O)c1cnc(nc1)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1

Formula: C19H19N5O4S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: R306465 is a potent inhibitor of HDAC1 and -8 (class I) in vitro. It potently inhibited cell proliferation of all main solid tumour indications, including colon, ovarian, breast, lung and prostate cancer cell lines with IC50 values ranging from 30 to 300 nM.

Molecular Weight: 413, 45

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