Product Overview
RA375 | T36902 | TargetMol Chemicals
CAS: 0
Smiles:
Formula: N/A
Pathway: Proteases/Proteasome|||Ubiquitination
Target: Proteasome
Receptor: N/A
Bioactivity: RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition of a chloroacetamide warhead[1].
Molecular Weight: N/A