Product Overview
Refametinib | T6636 | TargetMol Chemicals
CAS: 923032-37-5
Smiles: Fc1cc(OC)c(NS(=O)(=O)C2(CC2)C[C@H](O)CO)c(Nc2ccc(I)cc2F)c1F
Formula: C19H20F3IN2O5S
Pathway: MAPK
Target: MEK
Receptor: N/A
Bioactivity: Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
Molecular Weight: 572, 34
