Product Overview
Repotrectinib | T4071 | TargetMol Chemicals
CAS: 1802220-02-5
Smiles: C[C@H]1CNC(=O)c2cnn3ccc(N[C@H](C)c4cc(F)ccc4O1)nc23
Formula: C18H18FN5O2
Pathway: Angiogenesis|||Immunology/Inflammation|||Tyrosine Kinase/Adaptors
Target: Trk receptor|||ROS|||Src|||ALK
Receptor: N/A
Bioactivity: TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
Molecular Weight: 355, 373
