Product Overview
Reticuline | T4243 | TargetMol Chemicals
CAS: 485-19-8
Smiles: COc1ccc(C[C@@H]2N(C)CCc3cc(OC)c(O)cc23)cc1O
Formula: C19H23NO4
Pathway: Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel
Receptor: N/A
Bioactivity: Reticuline is a key compound in the biosynthetic pathway for isoquinoline alkaloids in plants, which include morphine, codeine and berberine. Reticuline possesses potent central nervous system depressant action, it (50-100 mg/kg i.p.) can produce alteration of behaviour pattern, prolongation of pentobarbital-induced sleep, reduction in motor coordination and D-amphetamine-induced hypermotility and suppression of the conditioned avoidance response. (S)-Reticuline can elicit vasorelaxation probably due to the blockade of the L-type voltage-dependent Ca(2+) current in rat aorta, the effect may contribute to the potential cardioprotective efficacy of (S)-reticuline.
Molecular Weight: 329, 4
