Product Overview
Rhapontigenin | T3776 | TargetMol Chemicals
CAS: 500-65-2
Smiles: COc1ccc(\C=C\c2cc(O)cc(O)c2)cc1O
Formula: C15H14O4
Pathway: Metabolism|||Microbiology/Virology
Target: P450|||Antibacterial|||Antifungal
Receptor: N/A
Bioactivity: Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).
Molecular Weight: 258, 273
