Product Overview
Rhosin | T16746 | TargetMol Chemicals
CAS: 1173671-63-0
Smiles: N[C@H](Cc1c[nH]c2ccccc12)C(=O)N\N=C\c1ccc2nccnc2c1
Formula: C20H18N6O
Pathway: Cell Cycle/Checkpoint
Target: Rho
Receptor: N/A
Bioactivity: Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.
Molecular Weight: 358, 405
