Product Overview
Rigosertib sodium | T5818 | TargetMol Chemicals
CAS: 592542-60-4
Smiles: COc1c(cc(cc1)CS(=O)(=O)/C=C/c1c(cc(cc1OC)OC)OC)NCC(=O)[O-].[Na+]
Formula: C21H24NNaO8S
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||PLK|||PI3K
Receptor: N/A
Bioactivity: Rigosertib, a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
Molecular Weight: 473, 47
