Product Overview
Ritodrine hydrochloride | T1433 | TargetMol Chemicals
CAS: 23239-51-2
Smiles: Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1
Formula: C17H21NO3·HCl
Pathway: GPCR/G Protein|||Neuroscience
Target: Adrenergic Receptor
Receptor: N/A
Bioactivity: Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a phenethylamine derivative with tocolytic activity. Specifically, ritodrine probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.
Molecular Weight: 323, 82
