Product Overview
RN-1747 | T16763 | TargetMol Chemicals
CAS: 1024448-59-6
Smiles: [O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)N1CCN(Cc2ccccc2)CC1
Formula: C17H18ClN3O4S
Pathway: Membrane transporter/Ion channel
Target: TRP/TRPV Channel
Receptor: N/A
Bioactivity: RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: hTRPV4 of 0.77 Ī¼M, mTRPV4 of 4.0 Ī¼M, and rTRPV4 of 4.1 Ī¼M). RN-1747 also antagonizes TRPM8 (IC50: 4 Ī¼M).
Molecular Weight: 395, 86
