Product Overview
Ro 31-8220 Mesylate | T6643 | TargetMol Chemicals
CAS: 138489-18-6
Smiles: CS(O)(=O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12
Formula: C26H27N5O5S2
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling
Target: PKC
Receptor: N/A
Bioactivity: Ro 31-8220 is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.
Molecular Weight: 553, 65
