Product Overview
Roblitinib | T4235 | TargetMol Chemicals
CAS: 1708971-55-4
Smiles: COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N
Formula: C25H30N8O4
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: FGFR
Receptor: N/A
Bioactivity: FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.
Molecular Weight: 506, 567