Roniciclib | T16784

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€301.00 - €4,150.00
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TMC-T16784
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Product Overview

Roniciclib | T16784 | TargetMol Chemicals

CAS: 1223498-69-8

Smiles: C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F

Formula: C18H21F3N4O3S

Pathway: Cell Cycle/Checkpoint

Target: CDK

Receptor: N/A

Bioactivity: Roniciclib is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.

Molecular Weight: 430, 45

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