Product Overview
Roniciclib | T16784 | TargetMol Chemicals
CAS: 1223498-69-8
Smiles: C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F
Formula: C18H21F3N4O3S
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: Roniciclib is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.
Molecular Weight: 430, 45