Product Overview
Rosiptor acetate | TQ0032L | TargetMol Chemicals
CAS: 782487-29-0
Smiles: CC(O)=O.C[C@]12CC[C@@H]([C@@H](CN)[C@@H]1CCC2=C)[C@@]1(C)CC[C@H](O)C[C@@H]1CO
Formula: C22H39NO4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Molecular Weight: 381, 557
