Product Overview
Rottlerin | T16791 | TargetMol Chemicals
CAS: 82-08-6
Smiles: CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)\C=C\c3ccccc3)c2O)c1O
Formula: C30H28O8
Pathway: Apoptosis|||Autophagy|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Microbiology/Virology|||Neuroscience|||Others|||Proteases/Proteasome|||Tyrosine Kinase/Adaptors
Target: CaMK|||Apoptosis|||Others|||HIV Protease|||PKA|||PKC|||Autophagy
Receptor: N/A
Bioactivity: Rottlerin is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα, β, γ of 30-42 μM, PKCε, η, ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.
Molecular Weight: 516, 546
