Product Overview
Ruboxistaurin hydrochloride | T3689 | TargetMol Chemicals
CAS: 169939-93-9
Smiles: Cl.CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21
Formula: C28H29ClN4O3
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling
Target: PKC
Receptor: N/A
Bioactivity: Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
Molecular Weight: 505, 02
