Product Overview
Ruboxistaurin mesylate | T3689L | TargetMol Chemicals
CAS: 192050-59-2
Smiles: CS(O)(=O)=O.CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21
Formula: C29H32N4O6S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
Molecular Weight: 564, 66
