Product Overview
RWJ-67657 | T16812 | TargetMol Chemicals
CAS: 215303-72-3
Smiles: OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1
Formula: C27H24FN3O
Pathway: MAPK
Target: p38 MAPK
Receptor: N/A
Bioactivity: RWJ-67657 is an orally active and selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively). RWJ-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect.
Molecular Weight: 425, 507
