Product Overview
RX-37 | T28630 | TargetMol Chemicals
CAS: 1627715-60-9
Smiles: COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)[nH]nc3C3CC3)c21
Formula: C24H23N5O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: RX-37 is a potent BET inhibitor with Ki values of 3.2-24.7 nM for BRD2, BRD3 and BRD4. RX-37 demonstrates high selectivity over other non-BET bromodomain-containing proteins. RX-37 potently and selectively inhibits cell growth in human acute leukemia cell lines harboring the rearranged mixed lineage leukemia 1 gene.
Molecular Weight: 413, 481
