Product Overview
(S)-Indoximod | T3S1967 | TargetMol Chemicals
CAS: 21339-55-9
Smiles: Cn1cc(C[C@H](N)C(O)=O)c2ccccc12
Formula: C12H14N2O2
Pathway: Metabolism|||Others
Target: Others|||Indoleamine 2, 3-Dioxygenase (IDO)
Receptor: N/A
Bioactivity: Abrine exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.
Molecular Weight: 218, 25
