Product Overview
(S, R, S)-AHPC-C5-COOH | T18667 | TargetMol Chemicals
CAS: 2267282-19-7
Smiles: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NCCCCCCC(O)=O)C(C)(C)C)cc1
Formula: C29H42N4O5S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: (S, R, S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases[1].
Molecular Weight: 558, 74
