Product Overview
(S, R, S)-AHPC-O-Ph-PEG1-NH2 | T18673 | TargetMol Chemicals
CAS: 2361117-24-8
Smiles: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCN)cc2)C(C)(C)C)cc1
Formula: C32H41N5O6S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: (S, R, S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is E3 ligase ligand-linker conjugate and incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S, R, S)-AHPC-O-Ph-PEG1-NH2 is used in PROTAC EED degrader-1. PROTAC EED degrader-1 is a PROTAC targeting EED with a pKD of 9.02[1].
Molecular Weight: 623, 77
