Product Overview
Sabutoclax | T6650 | TargetMol Chemicals
CAS: 1228108-65-3
Smiles: C[C@@H](CNC(=O)c1c(O)c(O)cc2c(O)c(c(C)cc12)-c1c(C)cc2c(C(=O)NC[C@H](C)c3ccccc3)c(O)c(O)cc2c1O)c1ccccc1
Formula: C42H40N2O8
Pathway: Angiogenesis|||Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: BCL|||Bcr-Abl
Receptor: N/A
Bioactivity: Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
Molecular Weight: 700, 788
