Product Overview
Sanggenon D | T4S1616 | TargetMol Chemicals
CAS: 81422-93-7
Smiles: CC(C)=CCC12Oc3cc(O)ccc3C1(O)Oc1cc(O)c(C3C=C(C)CC(C3C(=O)c3ccc(O)cc3O)c3ccc(O)cc3O)c(O)c1C2=O
Formula: C40H36O12
Pathway: Immunology/Inflammation|||Membrane transporter/Ion channel|||Neuroscience
Target: NOS|||COX|||GABA Receptor
Receptor: N/A
Bioactivity: Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 cells at > 10 uM; inhibition of nitric oxide production was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activity.
Molecular Weight: 708, 71
![[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/55083/51739/TargetMol-768x384__12443.1665998863__68435.1666081067.png?c=1 "[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P")
![[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P acetate](https://cdn11.bigcommerce.com/s-2kvb5rm600/images/stencil/500x659/products/55084/51740/TargetMol-768x384__12443.1665998863__89409.1666081068.png?c=1 "[D-Arg1, D-Phe5, D-Trp7, 9, Leu11]-Substance P acetate")
